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GHK-Cu is a naturally occurring copper-binding tripeptide (Gly-His-Lys) complexed with copper(II) ions. Found in human plasma, saliva, and urine, its concentration declines with age. It is extensively studied for skin regeneration, collagen synthesis, wound repair, and anti-inflammatory research.
GHK-Cu (glycyl-L-histidyl-L-lysine:copper(II)) is a naturally occurring tripeptide-copper complex first identified in human plasma by Dr. Loren Pickart in 1973. It is found in plasma, saliva, and urine, with plasma levels declining significantly with age — from approximately 200 ng/mL at age 20 to 80 ng/mL by age 60. GHK-Cu has a high affinity for copper(II) ions and has been the subject of extensive research for its roles in stimulating collagen and glycosaminoglycan synthesis, promoting tissue remodeling, activating wound repair processes, and modulating gene expression related to anti-inflammatory and antioxidant pathways.
| Molecular Weight | 403.93 g/mol |
| Sequence | Gly-His-Lys:Cu(II) |
| Purity | ≥99% (HPLC) |
| Physical Form | Lyophilized powder |
| Storage | -20°C, keep away from light and moisture |
Disclaimer: This product is intended for laboratory and research use only. Not for human or animal consumption. All handling should be conducted by qualified researchers in accordance with applicable regulations.
Every batch of GHK-Cu sold by CertPeptides is independently tested by a third-party laboratory. The Certificate of Analysis (COA) confirms identity, purity (≥99% via HPLC), and the absence of heavy metals and microbial contamination.
A COA is included with every order. You may also request a batch-specific COA through our contact page.