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IGF-1 LR3 – 1mg

IGF-1 LR3 – 1mg
Growth Hormone

IGF-1 LR3 – 1mg

$89.99

IGF-1 LR3 is a modified form of insulin-like growth factor-1 with an extended half-life due to an arginine substitution at position 3 and a 13-amino-acid N-terminal extension. It binds poorly to IGF-binding proteins, resulting in enhanced bioavailability in research models.

Molecular Weight:9,117.5 g/mol
Sequence:83 amino acid modified IGF-1
Purity:≥99% (HPLC)
Form:Lyophilized powder
Storage:-20°C
✔ Third-Party Tested
✔ COA Included
✔ 99%+ Purity
✔ Fast Shipping

Product Description

IGF-1 LR3 is a modified form of insulin-like growth factor-1 with an extended half-life due to an arginine substitution at position 3 and a 13-amino-acid N-terminal extension. It binds poorly to IGF-binding proteins, resulting in enhanced bioavailability in research models.

Specifications

Molecular Weight 9,117.5 g/mol
Sequence 83 amino acid modified IGF-1
Purity ≥99% (HPLC)
Physical Form Lyophilized powder
Storage -20°C, keep away from light and moisture

Research Applications

  • IGF-1 receptor binding and signaling studies
  • Muscle hypertrophy and anabolic pathway research
  • Cell proliferation and differentiation studies
  • Growth factor bioavailability and half-life research

Disclaimer: This product is intended for laboratory and research use only. Not for human or animal consumption. All handling should be conducted by qualified researchers in accordance with applicable regulations.

Certificate of Analysis

Every batch of IGF-1 LR3 sold by CertPeptides is independently tested by a third-party laboratory. The Certificate of Analysis (COA) confirms identity, purity (≥99% via HPLC), and the absence of heavy metals and microbial contamination.

A COA is included with every order. You may also request a batch-specific COA through our contact page.

Laboratory Product Information

📦 Includes

One (1) vial of IGF-1 LR3 lyophilized powder (1mg per vial), Certificate of Analysis (COA).

🔬 Purpose

IGF-1 LR3 (Long R3 Insulin-like Growth Factor-1) is an 83-amino-acid analog of native IGF-1 with an Arg³ substitution and 13-residue N-terminal extension that reduces IGF binding protein (IGFBP) affinity. It is used in in-vitro cell proliferation assays and IGF-1R signaling studies.

🧬 Ingredients

IGF-1 LR3 (Long R3 IGF-1) 83-amino-acid modified analog lyophilized powder, ≥98% purity (HPLC verified). No fillers, binders, or excipients.

🔬 Laboratory Handling Information

  • Molecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉ (approximate)
  • Molecular Weight: ~9,111 Da
  • Amino Acid Sequence: 83-amino-acid modified IGF-1 analog: 13-residue N-terminal extension + IGF-1 with Glu³→Arg³ substitution; three intramolecular disulfide bonds
  • Solubility: Soluble in sterile aqueous buffers (e.g., 10 mM HCl, PBS with 0.1% BSA); avoid alkaline pH
  • Storage: Store lyophilized product at 2–8°C; reconstituted aliquots at −20°C; add carrier protein (BSA) for dilute solutions
  • Literature Reference: Referenced at 1–100 nM for in-vitro cell proliferation, IGF-1R phosphorylation, and Akt/ERK signaling assays (PubMed: Francis et al., J Mol Endocrinol, 1992)

🚨 IMPORTANT — RESEARCH USE ONLY

FOR RESEARCH USE ONLY – NOT FOR HUMAN OR VETERINARY CONSUMPTION. Not intended for any in vivo use, therapeutic, or diagnostic purpose. No dosing or administration information provided or implied.

🚚 Shipping

Ships in temperature-controlled packaging via priority courier. Most orders ship within 24 hours on business days. Free shipping on orders over $150. Tracking number provided via email upon shipment.