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GLP-1 Agonists

Semaglutide – GLP-1 Receptor Agonist – 5mg

$74.99

Semaglutide is a GLP-1 receptor agonist with 94% structural homology to native human GLP-1. Features an acylated fatty acid chain that extends its biological half-life. A cornerstone of metabolic research worldwide.

Molecular Weight:~4113.58 g/mol
Purity:≥98% (HPLC)
Form:Lyophilized powder
Storage:-20°C
✔ Third-Party Tested
✔ COA Included
✔ 98%+ Purity
✔ Fast Shipping

Product Description

Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist with 94% structural homology to native human GLP-1. It features a key modification — an acylated fatty acid chain — that extends its biological half-life and enhances albumin binding. This peptide has become a cornerstone of metabolic research worldwide.

Specifications

Molecular Weight ~4113.58 g/mol
Purity ≥98% (HPLC)
Physical Form Lyophilized powder
Storage -20°C, keep away from light and moisture

Research Applications

  • GLP-1 receptor binding and signaling studies
  • Glucose homeostasis and insulin secretion research
  • Appetite and satiety pathway investigation
  • Long-acting peptide pharmacokinetics

Disclaimer: This product is intended for laboratory and research use only. Not for human or animal consumption. All handling should be conducted by qualified researchers in accordance with applicable regulations.

Certificate of Analysis

Every batch of Semaglutide sold by CertPeptides is independently tested by a third-party laboratory. The Certificate of Analysis (COA) confirms identity, purity (≥98% via HPLC), and the absence of heavy metals and microbial contamination.

A COA is included with every order. You may also request a batch-specific COA through our contact page.

Laboratory Product Information

📦 Includes

One (1) vial of Semaglutide lyophilized powder (5mg per vial), Certificate of Analysis (COA).

🔬 Purpose

Semaglutide is a long-acting GLP-1 receptor agonist with 94% structural homology to native GLP-1, incorporating modifications for enhanced stability and extended receptor engagement. It is utilized in in-vitro GLP-1R binding assays, cAMP dose–response studies, and beta-cell glucose-stimulated insulin secretion models.

🧬 Ingredients

Semaglutide modified GLP-1 analog (94% homology to native GLP-1, Aib⁸ substitution, Arg³⁴ substitution, C18 fatty diacid at Lys²⁶) lyophilized powder, ≥98% purity (HPLC verified). No fillers, binders, or excipients.

🔬 Laboratory Handling Information

  • Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉ (approximate; includes C18 fatty diacid–linker)
  • Molecular Weight: ~4113.58 Da
  • Amino Acid Sequence: 31-amino-acid modified GLP-1(7–37) analog; key modifications: Aib⁸, Arg³⁴, Lys²⁶-linked C18 fatty diacid via mini-PEG spacer
  • Solubility: Soluble in sterile aqueous buffers (e.g., bacteriostatic water, PBS) at concentrations suitable for in-vitro applications
  • Storage: Store lyophilized product at 2–8°C; reconstituted aliquots at −20°C; avoid repeated freeze-thaw cycles
  • Literature Reference: Referenced at 1–100 nM for in-vitro GLP-1R binding affinity, cAMP accumulation, and beta-cell GSIS assays (PubMed: Lau et al., J Med Chem, 2015)

🚨 IMPORTANT — RESEARCH USE ONLY

FOR RESEARCH USE ONLY – NOT FOR HUMAN OR VETERINARY CONSUMPTION. Not intended for any in vivo use, therapeutic, or diagnostic purpose. No dosing or administration information provided or implied.

🚚 Shipping

Ships in temperature-controlled packaging via priority courier. Most orders ship within 24 hours on business days. Free shipping on orders over $150. Tracking number provided via email upon shipment.